Folate deficiency and the utilization of folate drugs during early stages of pregnancy gets teratogenic and could result in many abnormalities into the development of fetus-like death. According to Blackburn, (2013), it’s probable that marginal folate status makes the probability of genetic defects in the mother more likely to happen. Genetic counseling and prenatal diagnosis become fundamental to ladies during the stage. Genetic defects identification gives room for counseling and further treatment if necessary to the patient and prevention of the defects from manifesting.
Serum marker testing benefits
Maternal serum screening test entails testing of the blood of a pregnant person to establish the potential of Edward syndrome, Down syndrome and neural tube defects that manifest within the unborn child. According to Loftus, (2014), the tests get conducted at least 10 weeks or 14-20 weeks depending on the applicable tests. Other tests include NIPT that’s non-invasive testing done during pregnancy to determine if the pregnancy gets affected by Trisomy 13, Edward Syndrome and Down syndrome. Additional tests that ought to get conducted during pregnancy include first-trimester prenatal screening tests, second-trimester prenatal screening tests, and amniocentesis.
Teratogens vulnerability
Teratogens entail elements that result in death defects and occur in the environment where the pregnant woman lives. Once conception takes place it requires six to nine days for implantation to happen. Schmerler, (2015) argued that the moment the egg gets fertilized it may relatively cross from the mother to the fetus. Teratogens might impact the fetus within 10 to 14 days following conception. Different organs get developed during the time, but it’s notable that certain organs remain sensitive throughout the pregnancy period, for instance, the central nervous system.
References:
- Blackburn, S. T. (2013). Maternal, fetal, & neonatal physiology: A clinical perspective. Amsterdam: Elsevier Saunders.
- Loftus, C. M. (2014). Neurosurgical aspects of pregnancy. Park Ridge, Ill: American Association of Neurological Surgeons.
- Schmerler, S. (2015). Lessons learned: Risk management issues in genetic counseling. New York: Springer.
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